Fotolia_56995117_MHyaluronic acid occurs naturally in the body and plays a critical role in retaining moisture in our skin. With age and environmental factors, hyaluronic acid gradually declines, and without enough moisture skin becomes loose, wrinkled and loses volume. Hyaluronic products penetrate deep and evenly into the skin. Wrinkle fillers such as Juvederm and Restylane® are used to add fullness and contour to deep creases such as the nasalabial folds. They plump out wrinkles, restore volume, shape and firmness to skin virtually instantly, and last between six and 12 months. Using Botox in conjunction with dermal fillers can produce optimum results in terms of volume and definition.